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HEYMACH, JOHN VICTOR

One or more keywords matched the following items that are connected to HEYMACH, JOHN VICTOR

Item Type	Name
Academic Article	A novel therapeutic combination for neuroblastoma: the vascular endothelial growth factor receptor/epidermal growth factor receptor/rearranged during transfection inhibitor vandetanib with 13-cis-retinoic acid.
Academic Article	Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
Academic Article	miR-200 Inhibits lung adenocarcinoma cell invasion and metastasis by targeting Flt1/VEGFR1.
Concept	Vascular Endothelial Growth Factor A
Concept	Vascular Endothelial Growth Factor Receptor-1
Concept	Vascular Endothelial Growth Factor Receptor-3
Concept	Endothelial Growth Factors
Concept	Vascular Endothelial Growth Factor Receptor-2
Concept	Vascular Endothelial Growth Factors
Concept	Receptors, Vascular Endothelial Growth Factor
Academic Article	Combining targeted agents: blocking the epidermal growth factor and vascular endothelial growth factor pathways.
Academic Article	Novel combinations based on epidermal growth factor receptor inhibition.
Academic Article	Vascular endothelial growth factor receptor tyrosine kinase inhibitors vandetanib (ZD6474) and AZD2171 in lung cancer.
Academic Article	Circulating biomarkers for vascular endothelial growth factor inhibitors in renal cell carcinoma.
Academic Article	Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance.
Academic Article	Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis.
Academic Article	Circulating biomarkers of response to sunitinib in gastroenteropancreatic neuroendocrine tumors: current data and clinical outlook.
Academic Article	Endothelial progenitor cells contribute to accelerated liver regeneration.
Academic Article	Inhibition of intra-abdominal adhesion formation with the angiogenesis inhibitor sunitinib.
Academic Article	Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2.
Academic Article	Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression.
Academic Article	Baseline vascular endothelial growth factor concentration as a potential predictive marker of benefit from vandetanib in non-small cell lung cancer.
Academic Article	Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma.
Academic Article	Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept.
Academic Article	Cytokines associated with toxicity in the treatment of recurrent glioblastoma with aflibercept.
Academic Article	Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity.
Academic Article	ZD6474--clinical experience to date.
Academic Article	Dual targeting of the vascular endothelial growth factor and epidermal growth factor receptor pathways: rationale and clinical applications for non-small-cell lung cancer.
Academic Article	Angiogenesis inhibitors for lung cancer: clinical developments and future directions.
Academic Article	Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.
Academic Article	Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge Conference assessing opportunities for combination therapy.
Academic Article	Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer.
Academic Article	A cytokine and angiogenic factor (CAF) analysis in plasma for selection of sorafenib therapy in patients with metastatic renal cell carcinoma.
Academic Article	The association of alternate VEGF ligands with resistance to anti-VEGF therapy in metastatic colorectal cancer.
Academic Article	Endostatin inhibits the vascular endothelial growth factor-induced mobilization of endothelial progenitor cells.
Academic Article	Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas.
Academic Article	Pharmacodynamic analysis of target inhibition and endothelial cell death in tumors treated with the vascular endothelial growth factor receptor antagonists SU5416 or SU6668.
Academic Article	Emerging antiangiogenic agents in lung cancer.
Academic Article	Vascular endothelial growth factor (VEGF) pathway.
Academic Article	Potent antitumor effects of ZD6474 on neuroblastoma via dual targeting of tumor cells and tumor endothelium.
Academic Article	Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells.
Academic Article	Distinct patterns of cytokine and angiogenic factor modulation and markers of benefit for vandetanib and/or chemotherapy in patients with non-small-cell lung cancer.
Academic Article	Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy.
Academic Article	Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype.
Academic Article	Antiangiogenic therapy and p53.
Academic Article	Vascular endothelial growth factor accelerates compensatory lung growth after unilateral pneumonectomy.
Academic Article	Phase 1-2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer.
Academic Article	Circulating biomarkers in advanced renal cell carcinoma: clinical applications.
Academic Article	VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy.
Academic Article	Vascular endothelial growth factor concentration as a predictive marker
Academic Article	KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib.
Academic Article	The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer.
Academic Article	Integrating cytokines and angiogenic factors and tumour bulk with selected clinical criteria improves determination of prognosis in advanced renal cell carcinoma.
Academic Article	Erlotinib plus either pazopanib or placebo in patients with previously treated advanced non-small cell lung cancer: A randomized, placebo-controlled phase 2 trial with correlated serum proteomic signatures.
Academic Article	Dual EGFR-VEGF Pathway Inhibition: A Promising Strategy for Patients With EGFR-Mutant NSCLC.
Academic Article	Altered Regulation of HIF-1a in Naive- and Drug-Resistant EGFR-Mutant NSCLC: Implications for a Vascular Endothelial Growth Factor-Dependent Phenotype.
Academic Article	Safety and activity of vandetanib in combination with everolimus in patients with advanced solid tumors: a phase I study.
Academic Article	Estrogen Promotes Resistance to Bevacizumab in Murine Models of NSCLC.
Academic Article	ARTEMIS highlights VEGF inhibitors as effective partners for EGFR TKIs in EGFR mutant NSCLC.
Academic Article	Molecular Mechanisms and Future Implications of VEGF/VEGFR in Cancer Therapy.

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Endothelial Growth Factors